Control of transcription initiation

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transcription initiation

Ve showed earlier [101 that the region of the bla promoter of Tn3 protected by the RHA-polymerase (REAP), has the normal size (about 60bp) at RJAP/promoter molar ratio r(2, but rises to about twice this extent as r increases. Ve confirm here that the species corresponding to normal and extended footprint distinguish by their electrophoretic mobilities. Furtheraore, inspection of the complexes b...

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Transcriptional Coactivator CBP Facilitates Transcription Initiation and Reinitiation of HTLV-I and Cyclin D2 Promoter

HTLV-I is the etiologic agent for adult T-cell leukemia/lymphoma (ATL) and HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP). Taxi, the major activator of this virus, is a 40- kDa (353 amino acid) phosphoprotein, predominantly localized in the nucleus of the host cell, which functions to trans-activate both viral and cellular promoters. Recently it has been shown that HTLV-I a...

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MinireviewViews of Transcription Initiation

to bind both core and DNA (Figure 1). 2 is essentially identical to E. coli 2, with an exposed region 2.2 helix Initiation of transcription is the first step in gene expredicted to form a primary interface with core and the pression and a major point of regulation. Recent strucregion 2.3–2.4 helix, which recognizes the 10 element tural studies reveal the nature of the initiating complex and con...

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Views of Transcription Initiation

Initiation of transcription is the first step in gene expression and a major point of regulation. Recent structural studies reveal the nature of the initiating complex and suggest new ways of accomplishing the processes required for initiation.

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Eukaryotic transcription initiation

Transcription is defined as the synthesis of RNA from a DNA template. In bacteria, transcription of all genes is catalysed by a single RNA polymerase, whereas in the eukaryotic nucleus, three different RNA polymerases — Pol I, Pol II and Pol III — carry out the synthesis of different classes of RNA. Pol I and Pol III transcribe a limited number of genes encoding ribosomal RNAs, transfer RNAs an...

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ژورنال

عنوان ژورنال: Journal of Biosciences

سال: 1993

ISSN: 0250-5991,0973-7138

DOI: 10.1007/bf02703034